The egg donors are anonymous and the potential recipient’s information is not
given to the donor or the outcome of the donor egg cycle itself. The recipient
does have available to them parts of the donor’s profile and psychological evaluation
but no specific identifying information. This allows the recipient to make the
best decision regarding potential donors.
Recipients and donors are matched using a list of specific requirements or characteristics
that they want from their donor such as physical attributes, education, or ethnicity.
Dr. Nichols/Payne and the PREG staff work very closely with donors and recipients
in helping make appropriate matches.
While going through an egg donor cycle, the donor and the recipient’s menstrual
cycle will be synchronized together usually with medications. When both the donor
and recipient are regulated, the donor starts fertility medications (daily injections)
to stimulate her ovaries to produce multiple eggs. The recipient during this time
will be monitored by using ultrasound and blood tests to make sure the lining
(endometrium) of her uterus is optimal for receiving embryos.
When the eggs are matured, they are harvested by way of an ultrasound guided
retrieval in which the donor is sedated and will feel no discomfort. After the
eggs are retrieved, the egg donor participation is over. The retrieved eggs will
then be fertilized in the lab with the recipient’s partner’s sperm by procedures
that offer the best fertilization results. The embryologist in the IVF lab will
determine the choice of fertilization method (IVF – in vitro fertilization versus
ICSI – intracytoplasmic sperm injection).
Three to five days after retrieval of the eggs the resultant embryo(s) will be
transferred to the recipient’s uterus. After the embryo transfer the recipient
will continue being monitored with blood work and a pregnancy test will be done
in about two weeks. If there is an excess of embryos the recipient will be given
the choice of freezing (cryopreservation). This will give the recipient additional
attempts to conceive.
Split Donor Cycles are also offered to appropriate patients to help share the expenses of a donor
cycle with another couple. A primary recipient will be matched for donation and
then a secondary recipient candidate will be found. The eggs retrieved from the
donor are split so that half of the eggs go to one recipient and half to the other.
A potential risk of a split donor cycle is that an insufficient number of eggs
are produced not allowing a split between the two recipients. In this case, all
the eggs would go to the primary recipient and the secondary recipient would be
dropped from the cycle and would be moved to a primary slot in another cycle.